2D Cobalt Oxyhydroxide Nanozymes Inhibit Inflammation by Targeting the NLRP3 Inflammasome (Adv. Funct. Mater. 27/2023)

Inflammatory Bowel Disease Relief In article number 2214693, Yunjiao Zhang and co-workers demonstrate 2D cobalt oxyhydroxide nanosheets (Co NSs) with excellent multienzyme-like activity as potential inhibitors of NLRP3 inflammasome pyroptosis. Owing to the robust reactive oxygen species scavenging oligomerization inhibiting ability, Co NSs block assembly activation inflammasome, thereby exhibiting anti-inflammation effect in colitis.